SURAWUT PRICHANOND, M.D.; JOHN L. SKOSEY, M.D., PH.D.
To the editor: Favreau, Tannenbaum, and Lough (Ann Intern Med 87:717-719, 1977) have reported three interesting cases of hepatic toxicity associated with gold therapy. Liver biopsies were done on two of their patients: one showed intrahepatic cholestasis and the other, ballooning of hepatocytes with minimal cholestasis. We wish to present the case of a patient who developed another type of liver damage during gold therapy.
A 44-year-old black woman with a 10-year history of seropositive rheumatoid arthritis developed gross hepatomegaly, generalized lymphadenopathy, and pulmonary infiltration after receiving a total dose of 135 mg of gold sodium thiomalate. She had also
PRICHANOND S, SKOSEY JL. Gold and Liver Biopsy. Ann Intern Med. ;88:579. doi: 10.7326/0003-4819-88-4-579_1
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Published: Ann Intern Med. 1978;88(4):579.
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