B. LARSEN, PH.D.; C. GOW, B.A., R.T.; W.H. MARSHALL, M.D., PH.D., M.R.C.P.
To the editor: Lymphocytotoxins have been described in patients with various diseases including systemic lupus erythematosus (1) and Hodgkin's disease (2). Since Mendius and associates (3) found a greatly increased prevalence of lymphocytotoxic antibodies in sera from relatives of patients with Hodgkin's disease (35.5%) compared with controls (8.6%) we hoped to extend their work by studying a familial aggregate of seven cases of Hodgkin's disease in Newfoundland (4, 5).
Sera from relatives of the patients were compared with sera from other persons from the same communities, but in this population there was no confirmation of the findings of Mendius and
LARSEN B, GOW C, MARSHALL W. Lymphocytotoxic Antibodies and Hodgkin's Disease. Ann Intern Med. ;88:718. doi: 10.7326/0003-4819-88-5-718_1
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Published: Ann Intern Med. 1978;88(5):718.
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