WENDELL A. WILSON, M.D., M.R.C.P.; J. G. PATRICK SISSONS, M.B., M.R.C.P.; OWEN S. MORGAN, M.D., M.R.C.P., F.A.C.P.
There is much interest in the lipoatrophic syndromes and their relation to autoimmune disorders, complement, and antibodies to membrane receptors (1-4). We report here the case of a patient with an unusual form of localised lipodystrophy characterized by bilateral symmetrical lipoatrophy within the third lumbar dermatome. Over 20 years this patient successively developed thyrotoxicosis, myasthenia gravis, and idiopathic thrombocytopenic purpura and also had bilateral optic atrophy and sensorineural deafness.
Our patient was first admitted to the University Hospital of the West Indies in 1955, at age 16, with palpitations, weight loss, and dyspnoea of 5 years' duration. Three years earlier
WILSON WA, SISSONS JGP, MORGAN OS. Multiple Autoimmune Diseases with Bilateral Optic Atrophy and Lipodystrophy. Ann Intern Med. ;89:72–73. doi: 10.7326/0003-4819-89-1-72
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Published: Ann Intern Med. 1978;89(1):72-73.
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