FREDERICK L. JONES JR., M.D., F.A.C.P.; RANDOLPH C. BLODGETT JR., M.D., F.A.C.P.
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To the editor: In 1971 we reported our observations on the unusual and not previously emphasized association of empyema and rheumatoid pleuropulmonary disease (Ann Intern Med 74:665-671, 1971). In that article we noted that of 10 persons with rheumatoid pleural effusions seen during a 5-year period, five had developed empyema and one had died of this complication. In contrast, no patient with neoplastic effusion or hydrothorax seen during this period had empyema. We speculated that causative factors which may have acted singly or in combination in the development of empyema included steroid therapy, decreased resistance to infection, chronic bronchopulmonary infections,
JONES FL, BLODGETT RC. Empyema and Rheumatoid Pleuropulmonary Disease. Ann Intern Med. ;89:139–140. doi: 10.7326/0003-4819-89-1-139_3
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Published: Ann Intern Med. 1978;89(1):139-140.
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