ELAINE S. JAFFE, M.D.; COSTAN W. BERARD, M.D.
It has been recognized for many years that some children with non-Hodgkin's lymphoma present with a characteristic distribution of supradiaphragmatic disease (1-6). Any combination of cervical, supraclavicular, or axillary lymph nodes may be involved, often with an anterior mediastinal mass or a pleural effusion containing neoplastic cells, or both. It has been known that a high percentage (30% to 50%) of such children developed acute leukemia if they have lived more than 2 to 3 months (3-6). Long before the discovery of T- and B-lymphoid cells, a relation was postulated between these tumors and the thymus gland (3). The progression
JAFFE ES, BERARD CW. Lymphoblastic Lymphoma, A Term Rekindled with New Precision. Ann Intern Med. ;89:415–417. doi: 10.7326/0003-4819-89-3-415
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Published: Ann Intern Med. 1978;89(3):415-417.
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