DAVID H. SPODICK, M.D., D.SC.; WILBERT ARONOW, M.D.; BERNARD LOWN, M.D.; BERNARD BARBER, PH.D.; VIRENDRA S. MATHUR, M.D.; HENRY BLACKBURN, M.D.; HENRY D. MCINTOSH, M.D.; DAVID BOYD, M.D.; THOMAS A. PRESTON, M.D.; C. RICHARD CONTI, M.D.; ARTHUR SELZER, M.D.; JAMES P. LOGERFO, M.D.; TIMOTHY TAKARO, M.D.
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To the editor: In theory, reviewers of scientific papers impose standards for acceptance based on the aim of all scientists—to report a true result. For therapeutic trials, a true result depends on appropriate design, that is, the results should reveal real treatment effects by measures that minimize biases in selecting patients and administering therapy. Acceptance of the results for publication implies merit, and without publication it is very difficult to establish a new treatment in practice. Medical journals thus become the filter through which appropriately studied modalities can go on to application but through which inappropriately studied modalities should not
SPODICK DH, ARONOW W, LOWN B, BARBER B, MATHUR VS, BLACKBURN H, et al. Standards for Therapeutic Trials. Ann Intern Med. ;89:422. doi: 10.7326/0003-4819-89-3-422_1
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Published: Ann Intern Med. 1978;89(3):422.
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