HARVEY J. COHEN, M.D., F.A.C.P.
To the editor: The treatment of primary amyloidosis continues to be a difficult problem. Although secondary amyloidosis sometimes can be reversed by treatment of the underlying process, most attempts at treating primary amyloidosis have been unsuccessful (1). In April 1975 we reported our experience with a patient who had widespread primary amyloidosis with a severe nephrotic syndrome. After chemotherapy she experienced a complete clinical remission, and by electron microscopy we were able to document actual disappearance of amyloid from her bone marrow (2). Since the appearance of that report I have had many requests for follow-up information on that patient
COHEN HJ. Combination Chemotherapy for Primary Amyloidosis Reconsidered.. Ann Intern Med. ;89:572–573. doi: 10.7326/0003-4819-89-4-572
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Published: Ann Intern Med. 1978;89(4):572-573.
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