STEPHEN E. STRAUS, M.D.
To the editor: The genus Candida includes a group of ubiquitous saprophytic fungi that frequently colonize the skin, mucous membranes, and gastrointestinal tract. These organisms are weakly pathogenic but in compromised hosts may result in serious localized or disseminated infections. Bayer and coauthors (1) have recently reviewed the published reports of candida meningitis. They concluded that the cumulative experience was too limited to permit specific recommendations regarding the appropriate nature and duration of therapy, but recovery appeared to be most frequently achieved with amphotericin B. Successfully treated persons generally received full doses of amphotericin B—the equivalent of about 35 to
STRAUS SE. Antifungal Therapy for Candidal Meningitis. Ann Intern Med. ;89:574–575. doi: 10.7326/0003-4819-89-4-574_3
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Published: Ann Intern Med. 1978;89(4):574-575.
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