JOHN S. TOBIN, M.D.
To the editor: I wish to comment on the report "Late Onset of Neuromuscular Block in Organophosphorus Poisoning" by Gadoth and Fisher in the May 1978 issue (Ann Intern Med 88:654-655, 1978).
The case described is not, in my opinion, a case of organophosphate intoxication, for the following reasons.
Labored breathing is not one of the early signs of this syndrome. The signs and symptoms of organophosphate intoxication are clearcut. The earliest are lightheadedness, dizziness, headache, and weakness, with hyperhydrosis, pallor, nausea, and blurring of vision. Respiratory depression is a late finding and is due to dysfunction of respiratory musculature.
TOBIN JS. Organophosphorus Poisoning. Ann Intern Med. 1978;89:579. doi: 10.7326/0003-4819-89-4-579_1
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Published: Ann Intern Med. 1978;89(4):579.
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