JACK ANSELL, M.D.; RICHARD S. BEASER, M.D.; LIBERTO PECHET, M.D., F.A.C.P.
Recent reports have emphasized the therapeutic success of exchange transfusion (1, 2), plasmapheresis (3), and plasma infusion (4) in the treatment of thrombotic thrombocytopenic purpura. We report a case of this disease showing the effectiveness of exchange transfusion and plasmapheresis and the failure of fresh frozen plasma infusion.
A 28-year-old white woman presented with severe headaches and fatigue. Physical examination showed a pale, lethargic woman with scattered petechiae. There was no lymphadenopathy or hepatosplenomegaly and the results of the remainder of the examination were unremarkable. Laboratory data showed an hematocrit of 23%, reticulocyte count of 13%, microangiopathic erythrocyte structure, and
ANSELL J, BEASER RS, PECHET L. Thrombotic Thrombocytopenic Purpura Fails to Respond to Fresh Frozen Plasma Infusion. Ann Intern Med. ;89:647–648. doi: 10.7326/0003-4819-89-5-647
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Published: Ann Intern Med. 1978;89(5_Part_1):647-648.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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