RICHARD G. PATTON, M.D.
To the editor: I have read with interest the paper by Yoo, Lessin, and Jensen (Ann Intern Med 88:753-757, 1978) that reports an attempt to quantitate the degree of bone marrow mast cell proliferation in various hematologic disorders. This was accomplished by a semiquantitative counting technique using a calibrated optical micrometre to examine bone marrow aspiration smears. Although this method appears to be reproducible for bone marrow aspiration smears, I question its validity for quantitation of bone marrow mast cell proliferation. It has been previously reported (1) in a subjective evaluation that bone marrow clot sections are far superior to
PATTON RG. Mast Cell Counts. Ann Intern Med. ;90:131. doi: 10.7326/0003-4819-90-1-131_1
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Published: Ann Intern Med. 1979;90(1):131.
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