JAMES S. GOODWIN, M.D.; JEAN M. GOODWIN, M.D.
To the editor: The most common neurologic manifestation of systemic lupus erythematosus is organic brain disease, which occurs in about 20% of patients (1). This high incidence of organic brain disease has been thought to be the result of episodes of cerebral vasculitis. We show here that scores of mental status testing in patients with lupus erythematosus decrease as a function of disease duration but are not related to whether the patient had a previous episode of clinical cerebritis. This would suggest that a chronic subclinical cerebritis might occur in many patients with lupus erythematosus.
We have studied 22 patients
GOODWIN JS, GOODWIN JM. Cerebritis in Lupus Erythematosus. Ann Intern Med. ;90:437–438. doi: 10.7326/0003-4819-90-3-437
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Published: Ann Intern Med. 1979;90(3):437-438.
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