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Stones in the urinary tract were for many years the province of the urologic surgeon who, by and large, was more concerned with safe and effective removal of the stone than with understanding why it occurred. The importance of disordered calcium metabolism in pathogenesis was firmly established by Albright, but most internists have regarded stones as clues to interesting diseases rather than a subject of study in their own right. Application of the techniques and concepts of physical chemistry to the problem of stone formation began about 25 years ago, but gained little momentum at first. Interest has been renewed
Calcium Urolithiasis.. Ann Intern Med. ;90:483–484. doi: 10.7326/0003-4819-90-3-483_3
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Published: Ann Intern Med. 1979;90(3):483-484.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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