DREW J. WINSTON, M.D.; WINSTON G. HO, M.D.; ROBERT PETER GALE, M.D., PH.D.
To the editor: Dr. Buckner and his colleagues from the Seattle Marrow Transplant Team in their article in the December 1978 issue (1) may have underestimated the importance and effectiveness of oral nonabsorbable antibiotics in their study of protective environments for bone-marrow transplant recipients. As these authors indicate, controlled studies by Schimpff and coworkers have shown that oral nonabsorbable antibiotics alone are as effective as nonabsorbable antibiotics plus laminar air flow isolation in preventing infections in patients with acute leukemia (2). Similarly, our study of prophylactic granulocyte transfusions plus oral nonabsorbable antibiotics versus oral nonabsorbable antibiotics alone in marrow transplant
WINSTON DJ, HO WG, GALE RP. Infection in Bone-Marrow Recipients. Ann Intern Med. 1979;90:715–716. doi: 10.7326/0003-4819-90-4-715_2
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Published: Ann Intern Med. 1979;90(4):715-716.
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