RICHARD L. SCHILSKY, M.D.; TOM ANDERSON, M.D.
We studied renal function and serum electrolytes in 51 patients receiving cisplatin chemotherapy by retrospectively reviewing the charts of 44 patients and prospectively following seven patients. Hypomagnesemia developed in 23 of 44 evaluable patients who were receiving cisplatin. We documented inappropriate renal magnesium wasting in four patients. Two patients required hospitalization for symptomatic hypomagnesemia. We conclude that cisplatin can induce a renal tubular defect in magnesium conservation and serious clinical syndromes of magnesium deficiency.
SCHILSKY RL, ANDERSON T. Hypomagnesemia and Renal Magnesium Wasting in Patients Receiving Cisplatin. Ann Intern Med. ;90:929–931. doi: 10.7326/0003-4819-90-6-929
Download citation file:
Published: Ann Intern Med. 1979;90(6):929-931.
Hematology/Oncology, Hospital Medicine, Nephrology.
Results provided by:
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use