J. KELLETT, M.D.; H. G. FRIESEN, M.D.
There have been four important medical advances that in a short time have combined to focus attention on the pituitary gland and disorders affecting it. These include a better appreciation of the neuroendocrine mechanisms that regulate pituitary hormone secretion, the recognition that hyperprolactinemia is implicated in approximately 25% of cases of secondary amenorrhea, improved radiologic techniques that allow the detection of pituitary microadenomas that previously went unrecognized, and restoration of normal endocrine function in a high percentage of patients after complete removal of these tumors using the transsphenoidal route. The early identification of these tumors is therefore important.
KELLETT J, FRIESEN HG. Bromocriptine and Pituitary Disorders. Ann Intern Med. ;90:980–982. doi: 10.7326/0003-4819-90-6-980
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Published: Ann Intern Med. 1979;90(6):980-982.
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