JOSEPH P. FIORE, M.D.
To the editor: I wish to offer several criticisms of the paper by Barton and Conrad in the February issue (1) on possible prolonged survival of leukemic patients who contract hepatitis.
The authors use SGOT elevation as the major diagnostic criterion for hepatitis but acknowledge that the causes of mild SGOT elevation in leukemia can be heterogeneous, including leukemic infiltration of the liver and chemotherapeutic drugs. The authors do not state what the mean SGOT elevation was, but apparently an SGOT concentration of 50 mU/mL (normal range, 10 to 40) for more than 1 week was considered elevated. Using such
FIORE JP. Hepatitis and Leukemia. Ann Intern Med. ;90:987–988. doi: 10.7326/0003-4819-90-6-987
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Published: Ann Intern Med. 1979;90(6):987-988.
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