HILARY A. BLACKLOCK, M.B., CH.B.; JAMES F. CLELAND; PAUL TAN, M.B., B.S.; VELAYUDHAN M. PILLAI, M.D.
To the editor: Although the hypereosinophilic syndrome has been well reviewed recently (1, 2), leukapheresis was not considered as a therapeutic option in these reports. In 1974 Ellman and colleagues (3) reported a single case of eosinophilia after the use of sulfisoxazole associated with myositis, myocarditis, and vasculitis. The clinical manifestations and the eosinophilia were relieved by leukapheresis on two successive days, removing 22 X 1010 and 9.6 X 1010 eosinophils, respectively. In 1977 Pineda and associates (4) reported the case of seven patients with moderate eosinophilia who were treated with leukapheresis from one (four cases) to four times. Yields
HILARY A. BLACKLOCK, JAMES F. CLELAND, PAUL TAN, VELAYUDHAN M. PILLAI. The Hypereosinophilic Syndrome and Leukapheresis. Ann Intern Med. 1979;91:650–651. doi: 10.7326/0003-4819-91-4-650_2
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Published: Ann Intern Med. 1979;91(4):650-651.
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