MICHAEL GOLDMAN, M.D.; DONALD HOLUB, M.D.
To the editor: The association of prolactinomas with the multiple endocrine adenomatosis type-1 complex, as suggested by Prosser's study (1) of three families, can be further substantiated by follow-up data from the original family described by Wermer (2) in 1954.
Four of the seven sisters affected with the syndrome had roentgenogram evidence of an intrasellar mass when first evaluated. Recently O.P., now 64 years of age, was admitted to the hospital and a prolactin of 455 ng/mL (normal female value, less than 25 ng/mL) found. The eldest sister, C.P., who previously had undergone pituitary irradiation, was contacted and her prolactin
GOLDMAN M, HOLUB D. Prolactinomas and the Multiple Endocrine Adenomatosis Type-1 Complex. Ann Intern Med. ;91:791–792. doi: 10.7326/0003-4819-91-5-791_2
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Published: Ann Intern Med. 1979;91(5):791-792.
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