JEFFREY L. MILLER, M.D.
To the editor: Hematologic side effects are known to occur as rare side effects of most nonsteroidal anti-inflammatory drugs. Pancytopenia or granulocytopenia has been observed with tolmetin sodium, naproxen, phenylbutazone, and indomethacin. To our knowledge, this side effect has not previously been reported with sulindac. We present a case of aplastic anemia apparently associated with use of sulindac.
A 54-year-old white man with classic ankylosing spondylitis also had apical pulmonary fibrosis and mild Addison's disease. For a recent flare of his sacroiliac pain, naproxen, 250 mg twice daily, was prescribed in March 1979 but was of no help and was
MILLER JL. Marrow Aplasia and Sulindac. Ann Intern Med. ;92:129. doi: 10.7326/0003-4819-92-1-129_1
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Published: Ann Intern Med. 1980;92(1):129.
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