MERLE A. SANDE, M.D.; W. MICHAEL SCHELD, M.D.
A penicillin-aminoglycoside regimen is accepted therapy for enterococcal endocarditis, but use of combinations of antibiotics in other forms of bacterial endocarditis is controversial. This review analyzes in-vitro, experimental animal model, and clinical studies of combination "synergistic" antibiotic treatment for enterococcal, viridans streptococcal, staphylococcal, and gram-negative aerobic bacillary endocarditis. Current recommendations for treatment of these entities are discussed.
SANDE MA, SCHELD WM. Combination Antibiotic Therapy of Bacterial Endocarditis. Ann Intern Med. ;92:390–395. doi: 10.7326/0003-4819-92-3-390
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Published: Ann Intern Med. 1980;92(3):390-395.
Cardiology, Endocarditis, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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