JOSHUA FEIBUSCH, M.D.; JOSE L. BARBOSA-SALDIVAR, M.D.; ROBERT S. BERNSTEIN, M.D.; GARY L. ROBERTSON, M.D.
Distant effects of benign or malignant tumors, mediated by humoral factors, are well known in the medical literature. Among these, the syndrome of inappropriate antidiuretic hormone secretion is frequently seen in malignant tumors. The opposite situation, that is, nephrogenic diabetes insipidus, or resistance to endogenous antidiuretic hormone, has never been described in association with a tumor. We report here what we believe to be the first such case.
A 47-year-old Hispanic man was admitted to St. Luke's Hospital Center in November 1977. The patient was well until January 1974, when he was first hospitalized for resection of an obstructing ileal
FEIBUSCH J, BARBOSA-SALDIVAR JL, BERNSTEIN RS, ROBERTSON GL. Tumor-Associated Nephrogenic Diabetes Insipidus. Ann Intern Med. 1980;92:797–798. doi: 10.7326/0003-4819-92-6-797
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Published: Ann Intern Med. 1980;92(6):797-798.
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