PAUL EPSTEIN, M.D.
Noninvasive diagnosis of the solitary pulmonary nodule continues to be a medically and economically important clinical problem. Radiographic detection of calcium in the center of the lesion is generally recognized as reliably indicating that it is benign. Conventional radiographic methods such as plain roentgenography and standard tomography can detect the calcification in many benign nodules. If the lesion appears uncalcified radiographically, invasive methods must be used to differentiate between benign and malignant disease. Developments in fiberoptic bronchoscopy and transthoracic needle biopsy have been helpful additions to diagnostic assessment, but biopsy, as well as thoracotomy, produce significant morbidity and occasional mortality
EPSTEIN P. Scanning the Solitary Pulmonary Nodule. Ann Intern Med. ;93:502. doi: 10.7326/0003-4819-93-3-502
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Published: Ann Intern Med. 1980;93(3):502.
Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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