GEORGE K. YORK, M.D.
To the editor: The article by Barza and Pauker (1) on the decision to biopsy, treat, or wait in patients with suspected herpes simplex encephalitis is a simulating guide to decision making in a difficult clinical situation. The analysis is both reasonable and correct. I believe, however, that the authors have arrived at an incorrect recommendation for patient management through inaccurate assumptions of the relative risks of brain biopsy and treatment with vidarabine. A more accurate decision may be made using the decision analysis provided by the authors by substituting more appropriate risks.
As pointed out, a major obstacle in
YORK GK. Herpes Simplex Encephalitis: Biopsy or Treatment?. Ann Intern Med. ;93:506–507. doi: 10.7326/0003-4819-93-3-506
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Published: Ann Intern Med. 1980;93(3):506-507.
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