JAMES B. PUCKETT, M.D.; M. ROBERT COOPER, M.D.
To the editor: Acute myelosclerosis is a rapidly fatal acute myeloproliferative disorder. Criteria for the diagnosis include acute onset of pancytopenia, bone marrow fibrosis, dysplasia and hyperplasia of all marrow cell lines, megakaryocyte prominence, minimal or absent nucleated and tear-drop erythrocytes and anisocytosis and poikilocytosis, and rare splenomegaly (1). We have recently seen a patient who developed acute myelosclerosis after successful treatment of a non-Hodgkin's lymphoma.
A 54-year-old woman was found to have a diffuse mixed lymphocytic-histiocytic lymphoma of the stomach in June 1977. A partial gastrectomy with Billroth II anastomosis and splenectomy were done. No other evidence of lymphoma
PUCKETT JB, COOPER MR. Acute Myelosclerosis After Treatment for Non-Hodgkin's Lymphoma. Ann Intern Med. ;93:510. doi: 10.7326/0003-4819-93-3-510_1
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Published: Ann Intern Med. 1980;93(3):510.
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