DOUGLAS LANIER Jr., M.D.; HERVE FAVRE, M.D.; ALLAN I. JACOB, M.D.; JACQUES J. BOURGOIGNIE, M.D.
Spontaneous and persistent hypercalcemia in chronic hemodialysis patients, although rare, is usually associated with secondary hyperparathyroidism (1). When other causes of hypercalcemia are absent parathyroidectomy is indicated (2). We report two chronic hemodialysis patients with severe hypercalcemia who were successfully treated with Cimetidine for more than 6 months.
Patient A is a 22-year-old black woman with sickle cell anemia in whom proteinuria and progressive renal failure developed in 1975. Chronic hemodialysis was initiated in January 1978. In February 1979, her serum calcium levels, which had ranged from 8.0 to 9.5 mg/dL, increased progressively over a 3month period to 9.9, 11.1,
LANIER D, FAVRE H, JACOB AI, BOURGOIGNIE JJ. Cimetidine Therapy for Severe Hypercalcemia in Two Chronic Hemodialysis Patients. Ann Intern Med. ;93:573–574. doi: 10.7326/0003-4819-93-4-573
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Published: Ann Intern Med. 1980;93(4):573-574.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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