LAWRENCE E. SAMELSON, M.D.; STEPHEN A. LERNER, M.D.; LEON RESNEKOV, M.D.; CONSTANTINE ANAGNOSTOPOULOS, M.D.
Fungal endocarditis responds poorly to medical therapy (1, 2). Therapeutic recommendations now include early surgery and aggressive use of antifungal drugs (3, 4). With increasing numbers of reports of late relapses, the definition of cure has now come into doubt (2, 5). We describe here a case of Candida parapsilosis endocarditis in a patient who relapsed after 7 years of suppressive therapy with flucytosine.
A 36-year-old female heroin abuser developed C. parapsilosis mitral valve endocarditis in September 1970. She needed excision of the infected valve and replacement with a #27 Björk-Shiley mitral valve prosthesis. After surgery the patient received 1.12
LAWRENCE E. SAMELSON, STEPHEN A. LERNER, LEON RESNEKOV, CONSTANTINE ANAGNOSTOPOULOS. Relapse of Candida parapsilosis Endocarditis After Long-Term Suppression with Flucytosine: Retreatment with Valve Replacement and Ketoconazole. Ann Intern Med. 1980;93:838–839. doi: 10.7326/0003-4819-93-6-838
Download citation file:
Published: Ann Intern Med. 1980;93(6):838-839.
Cardiology, Endocarditis, Infectious Disease.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use