JULIAN L. LOKEY, M.D.; J. JAY BAKER, M.D.; NORMA A. PRICE, M.D.; STANLEY H. WINOKUR, M.D.
Endodermal sinus tumor of the ovary is a malignant germ cell neoplasm affecting young women and children that historically has been associated with an extremely poor prognosis. Surgery alone or in combination with radiation therapy has resulted in a 3-year actuarial survival of 13% (1). Postoperative combination chemotherapy has resulted in improved survivals (2-5). We report here preliminary results using cisplatin, vinblastine, and bleomycin (PVB) in two patients after unilateral salpingo-oophorectomy for stage Ia disease.
Patient 1, a 28-year-old white woman, developed severe abdominal pain in the immediate postpartum period. Computerized axial tomography demonstrated a large abdominal mass. Laparotomy (26
LOKEY JL, BAKER JJ, PRICE NA, WINOKUR SH. Cisplatin, Vinblastine, and Bleomycin for Endodermal Sinus Tumor of the Ovary. Ann Intern Med. ;94:56–57. doi: 10.7326/0003-4819-94-1-56
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Published: Ann Intern Med. 1981;94(1):56-57.
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