JULIAN L. LOKEY, M.D.; J. JAY BAKER, M.D.; NORMA A. PRICE, M.D.; STANLEY H. WINOKUR, M.D.
Endodermal sinus tumor of the ovary is a malignant germ cell neoplasm affecting young women and children that historically has been associated with an extremely poor prognosis. Surgery alone or in combination with radiation therapy has resulted in a 3-year actuarial survival of 13% (1). Postoperative combination chemotherapy has resulted in improved survivals (2-5). We report here preliminary results using cisplatin, vinblastine, and bleomycin (PVB) in two patients after unilateral salpingo-oophorectomy for stage Ia disease.
Patient 1, a 28-year-old white woman, developed severe abdominal pain in the immediate postpartum period. Computerized axial tomography demonstrated a large abdominal mass. Laparotomy (26
JULIAN L. LOKEY, J. JAY BAKER, NORMA A. PRICE, STANLEY H. WINOKUR. Cisplatin, Vinblastine, and Bleomycin for Endodermal Sinus Tumor of the Ovary. Ann Intern Med. 1981;94:56–57. doi: 10.7326/0003-4819-94-1-56
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Published: Ann Intern Med. 1981;94(1):56-57.
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