R. BRADLEY SACK, M.D. SC.D.
Although Escherichia coli strains are recognized as the commonest facultative bacteria in the normal fecal flora and as highly virulent opportunistic pathogens when outside their normal ecologic niche, their importance in the production of actue diarrheal disease has not been appreciated until recently. Until about 10 years ago, E. coli strains were related to diarrheal disease only as enteropathogenic serotypes, known to cause nursery outbreaks of infantile diarrhea and thought to be of no importance in adult diarrheal disease. This concept has now drastically changed. There has been a tremendous expansion of knowledge of the role of E. coli as
SACK RB. Escherichia coli and Acute Diarrheal Disease. Ann Intern Med. 1981;94:129–130. doi: 10.7326/0003-4819-94-1-129
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Published: Ann Intern Med. 1981;94(1):129-130.
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