DONALD C. DOLL, M.D.; KINDER J. DOLL, M.D.
To the editor: Dr. Finegold has written an excellent review of the therapeutic uses and indications for metronidazole (1). We wish to add another potential use for this drug: the treatment of malodorous tumors.
We have recently seen two patients with ulcerating breast cancer with a strong, foul odor. This odor was most distressing to the patients as well as to the hospital personnel who attended them. Because this offensive smell was reminiscent of anaerobic infection metronidazole was given, at 250 mg orally, three times a day for 10 days. Both patients had complete amelioration of their odor. Other authors
DOLL DC, DOLL KJ. Malodorous Tumors and Metronidazole. Ann Intern Med. ;94:139–140. doi: 10.7326/0003-4819-94-1-139_2
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Published: Ann Intern Med. 1981;94(1):139-140.
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