P. N. DURRINGTON, M.D.; J. E. MacIVER, M.D.; G. HOLDSWORTH, Ph.D.; D. J. GALTON, M.D.
Both type I and type V hyperlipoproteinemia are characterized by hyperchylomicronemia (1). In type I hyperlipoproteinemia levels of no other serum lipoproteins are increased, whereas in type V hyperlipoproteinemia very low density lipoprotein levels are also elevated. Recognized complications of both disorders include episodes of abdominal pain, acute pancreatitis, splenomegaly, and splenic infarction (1). We report a middle-aged patient with the type V phenotype who was unusual because she had pancytopenia secondary to hypersplenism, a complication previously believed not to occur with splenomegaly due to hyperchylomicronemia (1). She also had a profound deficiency of lipoprotein lipase activity in both postheparin
P. N. DURRINGTON, J. E. MacIVER, G. HOLDSWORTH, D. J. GALTON. Severe Hypertriglyceridemia Associated with Pancytopenia and Lipoprotein Lipase Deficiency. Ann Intern Med. 1981;94:211–212. doi: 10.7326/0003-4819-94-2-211
Download citation file:
Published: Ann Intern Med. 1981;94(2):211-212.
Cardiology, Coronary Risk Factors, Dyslipidemia, Hematology/Oncology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use