GARY M. KAMMER, M.D.
To the editor: In their study of vasculitis complicating rheumatoid arthritis, Abel and associates (1) pointed out that circulating immune complexes are temporarily associated with clinical features of vasculitis and that circulating immune complexes may, in part, mediate the pathophysiology of rheumatoid arthritis. Thus, this study confirms previous work that showed circulating immune complexes in rheumatoid arthritis, noted the general relation between disease activity and the presence of complexes, and suggested a role for such complexes in rheumatoid arthritis (2, 3).
However, this paper also indirectly raises the issue of the actual clinical utility of immune complex assays in the
KAMMER GM. Immune Complex Assays in Rheumatoid Disorders. Ann Intern Med. ;94:275. doi: 10.7326/0003-4819-94-2-275_1
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Published: Ann Intern Med. 1981;94(2):275.
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