PAUL KATZ, M.D.; ANTHONY S. FAUCI, M.D.; HENRY YEAGER Jr., M.D.; BERNARD M. REEN, M.D.
Over the past several years, attempts to develop specific serologic tests for diagnosing sarcoidosis have been the focus of intense investigation. That serum levels of angiotensin-converting enzyme (1) and lysozyme (2) are elevated in this disorder has been established, although the diagnostic value of these tests has been recently questioned (3, 4). The present study was undertaken to ascertain the levels of serum angiotensin-converting enzyme and lysozyme in noninfectious granulomatous disorders of unknown cause other than sarcoidosis.
Serum samples from eight patients with granulomatous hepatitis, nine with Wegener's granulomatosis, three with lymphomatoid granulomatosis, and four with midline granuloma were stored
KATZ P, FAUCI AS, YEAGER H, REEN BM. Serum Angiotensin-Converting Enzyme and Lysozyme in Granulomatous Diseases of Unknown Cause. Ann Intern Med. ;94:359–360. doi: 10.7326/0003-4819-94-3-359
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Published: Ann Intern Med. 1981;94(3):359-360.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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