ROBERT C. SMALLRIDGE, M.D.; LEONARD WARTOFSKY, M.D.; KENNETH D. BURMAN, M.D.
To the editor: Low-dose external irradiation is frequently associated with subsequent thyroid malignancy (1). Although Schimpff and colleagues (2) state that no patients have developed thyroid cancer after higher dose (> 2000 rad) therapy for Hodgkin's disease, this occurrence has been reported by others (3, 4). We have recently seen two patients with Hodgkin's disease who subsequently developed thyroid carcinoma. These patients are of particular interest because radiation therapy was used in only one of them, emphasizing the fact that other factors could be playing a role in tumor development.
A 54-year-old man developed stage IIIB Hodgkin's disease (mixed cellular
SMALLRIDGE RC, WARTOFSKY L, BURMAN KD. Thyroid Carcinoma and Hodgkin's Disease. Ann Intern Med. ;94:412–413. doi: 10.7326/0003-4819-94-3-412_2
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Published: Ann Intern Med. 1981;94(3):412-413.
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