THOMAS G. OLSEN, M.D.
To the editor: For the past 20 years there have been sporadic reports in the literature of flares of psoriasis coincident with the intake of antimalarial drugs (1-3). Nevertheless, the relation remains controversial because of the lack of prospective data and reports documenting actual improvement of psoriasis, arthritis, or both while patients are taking antimalarials (4, 5). I recently saw the following case.
A 58-year-old man with a 9-year history of psoriasis whose disease was well controlled on twice-weekly PUVA (oral methoxsalen and high-intensity long-wave ultraviolet light) treatments, experienced a flare of the skin disease while traveling in Brazil. Two
OLSEN TG. Chloroquine and Psoriasis. Ann Intern Med. ;94:546–547. doi: 10.7326/0003-4819-94-4-546_2
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Published: Ann Intern Med. 1981;94(4_Part_1):546-547.
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