ADEL G. FAM, M.D.; THOMAS W. PATON, PHARM. D.; DONALD H. COWAN, M.D.
To the editor: Studies describing the various cutaneous reactions associated with gold therapy for rheumatoid arthritis have not included herpes zoster (1). Known precipitants of zoster include lymphomas, other malignancies, immunosuppressive therapy, and heavy metal poisoning or therapy (2-5). We have observed an unusually high prevalence of herpes zoster in patients with rheumatoid arthritis treated with gold salts.
The records of 159 patients (110 women and 49 men) with rheumatoid arthritis who were receiving gold sodium thiomalate while hospitalized at the rheumatic disease unit during 4 years (1975 to 1978) were reviewed. A relation between chrysotherapy and zoster was suggested
FAM AG, PATON TW, COWAN DH. Herpes Zoster During Gold Therapy. Ann Intern Med. ;94:712–713. doi: 10.7326/0003-4819-94-5-712
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Published: Ann Intern Med. 1981;94(5):712-713.
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