KENNETH S. WILSON, M.B.; SKARIA ALEXANDER, M.B.
To the editor: The recently published review by Weiss and Bruno (1) prompts us to report a second case of type 1 hypersensitivity to intravenous mechlorethamine.
A 52-year-old white woman had upper abdominal discomfort and night sweats in June 1976. She had no history of allergies. Physical examination showed generalized superficial lymphadenopathy, hepatosplenomegaly and a mass of retroperitoneal lymph nodes in the left iliac fossa. Lymph node biopsy showed nodular well differentiated lymphocytic lymphoma. Bone marrow biopsy was positive for lymphocytic lymphoma. Initial hemoglobin was 12.2 g/dL; leukocytes, 9800/mm3 (68% neutrophils, 23% lymphocytes), and platelets 162 000/mm3. Treatment with intravenous
WILSON KS, ALEXANDER S. Hypersensitivity to Mechlorethamine. Ann Intern Med. ;94:823. doi: 10.7326/0003-4819-94-6-823_2
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Published: Ann Intern Med. 1981;94(6):823.
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