LEONARD J. DEFTOS, M.D.; BRIAN P. FIRST, M.D.
Calcitonin is a peptide hormone produced by the C-cells of the thyroid gland. Its main biological effect is to inhibit the resorption of bone. This effect, in combination with a calciuric action of calcitonin, can produce a lowering of blood calcium. These biological effects of calcitonin have made it useful in the treatment of hypercalcemic and hyperresorptive disorders.
LEONARD J. DEFTOS, BRIAN P. FIRST. Drugs Five Years Later: Calcitonin as a Drug. Ann Intern Med. 1981;95:192–197. doi: 10.7326/0003-4819-95-2-192
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Published: Ann Intern Med. 1981;95(2):192-197.
Endocrine and Metabolism, Thyroid Disorders.
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