IAN D. HAY, M.B., Ph.D.; DANIEL S. DUICK, M.D.; RONALD E. VLIETSTRA, M.D.; JAMES D. MALONEY, M.D.; JAMES R. PLUTH, M.D.
Hypothyroid patients with disabling angina pectoris present a difficult problem in clinical management (1). Because rapid thyroid hormone replacement can aggravate a pre-existing anginal syndrome, the current therapeutic regimen in most hypothyroid patients with anginal distress is incomplete replacement, resulting in some degree of residual hypothyroidism (2, 3). Aortocoronary bypass graft surgery has provided a means of alleviating angina pectoris, but whether hypothyroid patients should undergo cautious thyroid replacement before cardiac catheterization and bypass graft surgery remains unclear (4). To address this problem, we reviewed our experience since 1970 with hypothyroid patients who had coronary artery surgery for incapacitating angina
HAY ID, DUICK DS, VLIETSTRA RE, MALONEY JD, PLUTH JR. Thyroxine Therapy in Hypothyroid Patients Undergoing Coronary Revascularization: A Retrospective Analysis. Ann Intern Med. ;95:456–457. doi: 10.7326/0003-4819-95-4-456
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Published: Ann Intern Med. 1981;95(4):456-457.
Endocrine and Metabolism, Thyroid Disorders.
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