PAOLO PASQUA; ANTONIO CRAXI; LUIGI PAGLIARA
To the editor: Floctafenine (idarac), a nonnarcotic analgesic of the hydroxyquinoline group, is used widely because of its minimal untoward side effects, even in high-risk patients. In particular, no sleep-inducing effect has been reported from animal or human studies (1, 2). In our department, in which mainly patients with chronic liver diseases are seen, it has therefore been used as a safe first-choice analgesic. We have recently studied an episode of coma in a cirrhotic patient in which floctafenine could be causally involved.
A 53-year-old alcoholic patient with cirrhosis, chronic pancreatitis, and duodenal ulcer was admitted to our department because
PASQUA P, CRAXI A, PAGLIARA L. Floctafenine and Coma in Cirrhosis. Ann Intern Med. ;96:253. doi: 10.7326/0003-4819-96-2-253_1
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Published: Ann Intern Med. 1982;96(2):253.
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