CARL F. MYERS, M.D.; WILLIAM B. ERSHLER, M.D.; MARK A. TANNENBAUM, A.B.; RICHARD BARTH, M.D.
To the editor: Keshgegian and Wheeler (1) have recently demonstrated the presence of estrogen receptors in two carcinoid tumors. Other investigators (2) reported symptomatic improvement with tamoxifen therapy in a patient with carcinoid syndrome, although objective evidence of disease regression was not presented. We report a patient who obtained a significant objective response to tamoxifen therapy.
A 59-year-old man had had intermittent diarrhea and crampy abdominal pain diagnosed as "colitis" 15 years before admission. These symptoms had remained stable until 6 years before admission when his diarrhea had increased to once or twice a day and intermittent hot flashes and
MYERS CF, ERSHLER WB, TANNENBAUM MA, BARTH R. Tamoxifen and Carcinoid Tumor. Ann Intern Med. ;96:383. doi: 10.7326/0003-4819-96-3-383_1
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Published: Ann Intern Med. 1982;96(3):383.
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