DAVID MERZ, M.D.
To the editor: After an extensive analysis of the predictive value of the HLA-B27 test, Kahn and Kahn (1) examined the utility of the test in four cases. They could provide only one case history, that of Patient 3, where the test clearly appeared to be useful. Unfortunately, they also implied that the test could be useful in patients whose cases are similar to that of Patient 4. Khan and Khan suggested that, because the sensitivity of the test was higher than the sensitivity of another more specific diagnostic procedure, the HLA-B27 test would be better for "excluding" the diagnosis
MERZ D. Non-Utility of the HLA-B27 Test. Ann Intern Med. ;96:383–384. doi: 10.7326/0003-4819-96-3-383_3
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Published: Ann Intern Med. 1982;96(3):383-384.
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