JONATHAN R. DIAMOND, M.D.; DAVID C. YOBURN, M.D.
Measurement of the fractional excretion of sodium has been recommended as a useful clinical tool in evaluating acute renal failure. Six patients with nonoliguric acute renal failure had a fractional excretion of sodium less than or equal to 1.0%; these patients had severe liver dysfunction, which suggested a sodium-avid state. A review of the literature showed that in patients with other sodium-avid states (congestive heart failure, nephrotic syndrome, and burns) the fractional excretion of sodium was frequently less than or equal to 1.0%. The fractional excretion of sodium is thus a less useful diagnostic test in patients whose clinical state makes them sodium avid.
DIAMOND JR, YOBURN DC. Nonoliguric Acute Renal Failure Associated with a Low Fractional Excretion of Sodium. Ann Intern Med. ;96:597–600. doi: 10.7326/0003-4819-96-5-597
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Published: Ann Intern Med. 1982;96(5):597-600.
Acute Kidney Injury, Nephrology.
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