SCOTT J. RATNER, M.D.
To the editor: Zomepirac sodium, a recently introduced non-steroidal anti-inflammatory drug, has been heavily promoted for use as an analgesic (1). I report a case of acute renal failure that was likely due to the use of zomepirac sodium.
A previously healthy 26-year-old male physician who was taking no prescribed or over-the-counter medications took one 50-mg tablet of zomepirac sodium for relief of a simple headache. He awoke the next morning (approximately 12 hours after ingestion) feeling nauseated and weak but went to work. During the day nausea persisted, diffuse abdominal and flank pains developed, and weakness progressed, forcing him
RATNER SJ. Zomepirac and Renal Failure. Ann Intern Med. ;96:793. doi: 10.7326/0003-4819-96-6-793_1
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Published: Ann Intern Med. 1982;96(6_part_1):793.
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