BRIAN J. MURRAY, M.D.
To the editor: In their article on infectious mononucleosis Aronson and associates (1) make some constructive criticisms of their own study, but a few additional comments merit consideration. The sole determinant for deciding if patients with a sore throat had infectious mononucleosis appears to have been detection of a heterophil antibody. They ignored, for classification purposes, the presence of atypical lymphocytes and lymphocytosis, which is so characteristic of infectious mononucleosis (2). I hesitate to accept that all 15 patients had infectious mononucleosis, when in fact only four had the typical lymphocytosis.
Aronson and associates touch on the possibility of a
MURRAY BJ. Infectious Mononucleosis. Ann Intern Med. ;97:148. doi: 10.7326/0003-4819-97-1-148_1
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Published: Ann Intern Med. 1982;97(1):148.
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