YAAKOV NAPARSTEK, M.D.; MICHA LEVY, M.D.
To the editor: In the detailed analysis in Aronson and associates' report (1) of the clinical features in patients with or without heterophil antibodies, one important observation seems to be missing—the occurrence of rash. Rash was reported to appear in 16% of patients with infectious mononucleosis not receiving antibiotic therapy and in up to 95% of patients with infectious mononucleosis receiving ampicillin therapy (2), yet it is a rare feature in streptococcal sore throat unless heralding scarlet fever. The general incidence of ampicillin and penicillin rash is estimated to be 7.7% and 2.7%, respectively (3).
The recognition and correct attribution
NAPARSTEK Y, LEVY M. Rash and Infectious Mononucleosis. Ann Intern Med. ;97:284. doi: 10.7326/0003-4819-97-2-284_1
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Published: Ann Intern Med. 1982;97(2):284.
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