SANJIV KAUL, M.D.; MAYLENE WONG, M.D.; BRAMAH N. SINGH, M.D., D. PHIL.; ROBERT S. HEPLER, M.D.
To the editor: Nonspecific visual disturbances have been reported with the use of most beta-adrenergic blocking agents (1, 2). Serious ocular disorders, however, have not been described for any of these compounds except in the case of practolol (3). Nadolol, a long-acting beta-antagonist has been marketed in the United States since January 1980. Visual disturbances have been reported with this drug but objective evidence of serious ocular disturbance has not been documented (4, 5).
A 58-year-old white man was started on 40 mg of nadolol a day for hypertension. After the first dose the patient had diplopia while playing tennis.
KAUL S, WONG M, SINGH BN, HEPLER RS. Nadolol and Papilledema. Ann Intern Med. ;97:454. doi: 10.7326/0003-4819-97-3-454_3
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Published: Ann Intern Med. 1982;97(3):454.
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