WILLIAM J. CACCESE, M.D.; MATTHEW J. MCKINLEY, M.D.; LAWRENCE S. KRYLE, M.D.; RICHARD L. BRONZO, M.D.
To the editor: We read with interest the recent editorial on sucralfate (1). Since its approval by the FDA, we have used sucralfate to treat patients with peptic ulcer disease. Because of its low incidence of side effects (2), we often use sucralfate in treating peptic ulcer disease in patients who might be at a higher risk of developing adverse effects from cimetidine (3). Controlled trials show that sucralfate results in ulcer healing as often as cimetidine (4). We report a case of peptic ulcer disease treated with sucralfate complicated by perforation while on therapy.
A 73-year-old woman was evaluated
CACCESE WJ, MCKINLEY MJ, KRYLE LS, BRONZO RL. Sucralfate and Ulcer Perforation. Ann Intern Med. ;97:619–620. doi: 10.7326/0003-4819-97-4-619_3
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Published: Ann Intern Med. 1982;97(4):619-620.
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