SIMON SMITZ, M.D.; JEAN-JACQUES LEGROS, M.D.; MARC LE MAIRE, PH.D.
To the editor: We write to report beneficial actions of naloxone in two patients.
A 54-year-old woman with a 5-year history of generalised itch of unknown origin was given a naloxone infusion (1.6 mg/h during 4 hours). During the days after this infusion, the itch gradually disappeared. Her perception of painful stimuli was reduced and remained unmodified by the treatment.
A 39-year-old woman had a 25-year history of asthma, chronic urticaria, and angioedema. No specific allergy had been shown. Because of frequent episodes of laryngeal obstruction, glucocorticosteroids were administered for more than 10 years. After a similar naloxone infusion, clinical
SMITZ S, LEGROS J, MAIRE ML. Naloxone, Itch, Asthma, Urticaria, and Angioedema. Ann Intern Med. ;97:788–789. doi: 10.7326/0003-4819-97-5-788_3
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Published: Ann Intern Med. 1982;97(5):788-789.
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