LEWIS A. DUNCAN, M.D.; SAMUEL P. MARYNICK, M.D.
To the editor: In the September 1980 issue (1) we reported a case of glucagonoma metastatic to liver that had been in remission clinically after dacarbazine (DTIC) chemotherapy for 18 months. At the time of the report the patient was still in remission. This patient was the third reported to have malignant glucagonoma that had responded to DTIC. Our patient had not responded to streptozocin as a single agent given before DTIC therapy.
Alternate-month DTIC maintenance chemotherapy, 200 mg/m2 body surface area · d for 5 days, was continued from September to December 1980. In December 1980 the patient developed
LEWIS A. DUNCAN, SAMUEL P. MARYNICK. Glucagonoma and Dacarbazine. Ann Intern Med. 1982;97:930. doi: 10.7326/0003-4819-97-6-930_1
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Published: Ann Intern Med. 1982;97(6):930.
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